Then you'd have people not knowing what we're going forward from since WB has kept B5 buried with Jimmy Hoffa and Shelly Miscavige. This isn't Star Trek that was well known before being reintroduced as a movie and a spinoff. And Season 5 wasn't terrible. It was aired terribly where Byron's 5 main episodes stretched over 4 months, but the Drakh infiltration of the Centauri was 60% of the season and shown straight through the end of the year.

Funny that you mention it, but the Crusade would have cured the plague in Season 2 and seen the ship turn into renegades because of the Clark faction securing more power in Earth politics.