People have been touting one or another form of chelation for decades. The theory is that because calcium is found in atherosclerotic plaque, removing the calcium will open up the arteries and prevent heart attacks.
There is zero evidence to support this theory, which is a simplistic and wrong concept of how atherosclerosis works.
As mentioned above, EDTA (the chelating agent) can cause very serious adverse effects, including kidney failure.

As 12131 said, there are no secrets. Don’t smoke, drink alcohol in moderation, maintain a healthy weight, exercise at least moderately several times a week.

Keep blood pressure and blood sugar controlled.
For those at increased risk of heart disease, low-dose aspirin and statins reduce risk (beyond effects on lowering cholesterol).

Don’t live in isolation: it’s especially bad for older men.