If you have Neuropathy or a family member has it, you probably understand the amount of pain it can create, and you will live on pregabalin or gabapentin for life so the subject is important.

Had an ingrown nail fixed today, in the course of it my podiatrist asked my about neuropathy and if its something I have been dealing with, which is yes.

My dad has it, his dad, and now me, Type 2, and I take metformin. There is evidence that metformin can make neuropathy worse as long term use lowers vitamin B12 absorption and that leads to damage to the myelin sheath covering nerves.

He recommended EBN Medicals EB-N6 which is a supplement, $150 for 90 days, no insurance will cover it so it's out of pocket.

https://ebmmedical.com/patients/

Here's the specifications:

EB-N6 (including EB-N6DR) contains the following active ingredients per serving (typically 2 capsules daily):

EBM Medical +1

• L-Methylfolate Calcium: 6 mg (bioactive folate)
  
• Methylcobalamin: 4 mg (bioactive vitamin B12)
  
• Pyridoxal 5′-Phosphate (P5P): 70 mg (bioactive vitamin B6)
  
• Alpha Lipoic Acid: 600 mg (antioxidant)
  
• Benfotiamine: 300 mg (fat-soluble thiamine / vitamin B1 derivative

I'm generally not a supplement fan, especially ones where you have to "subscribe" give them a CC and get shipments until you say uncle. However, if it works then it's worth it to try...

The doctor calls in the script to them, they call you back (already done so) and you agree to get on the program, which I've not done

Wondered if anyone here is experiencing Never induced pain, like neuropathy, how you deal with it, have you ever used EB-N6

My podiatrist says it has been used by many patients who have experienced neuropathy either from Diabetes or Cancer Treatments or some physical malady that created it in their bodies and have had good results.

It will either, reduce the pain and stop the process, reduce the increase in the amount of nerve damage so the future isn't as bad as if you didn't take the EB-N6.

The other part of me says, what's so special about their formulation of B12 and B6 that I can't get that same from a multi vitamin that covers both, or, taking B12 and B6 vitamins...

Sorry you're dealing with this HRK. It is painful as hell. I deal with it off and on, but mine is chemo induced. I'll get it 3-4 days after infusion but only lasting a day or 2. Wish I could help but I just muddle through until it goes away.

Increasing circulation by keeping my feet warm, massage, and compression helps me.
Also making sure I have a high arch insole that supports my feet really helps. Superfeet brand insoles are less than $100.00 a pair and are well worth the cost.

A monthly pedicure comes with a massage of the feet and lower legs, and if you are lucky enough to get the old Asian lady she will work your feet where while she is doing it you will hurt bad, but when she is done it feels so good. Reflexology on your feet also is beneficial as the Reflexologist can tell you what is going on with your body when she hits a point that causes you discomfort.

These are what I use for neuropathy in my feet.

quote:

Originally posted by pace40:
Sorry you're dealing with this HRK. It is painful as hell. I deal with it off and on, but mine is chemo induced. I'll get it 3-4 days after infusion but only lasting a day or 2. Wish I could help but I just muddle through until it goes away.

Sorry you're dealing with it as well. He said that he's prescribed this to his patients undergoing Chemo induced Neuropathy and it's really helped them, you may want to look into it, hopefully we'll get some good intel here as is normal on SF

I take B12 that's about it. I find walking helps for some reason so I do a couple of miles on the treadmill each day.

I have ideopathic neuropathy in my feet and shins. I use lidocaine to help me sleep as needed. During the day, I just grin and bear it.

Have been taking the EB-N6 for a month or so, can't tell a difference so far, but PN varies so much between people I would not let that deter you. Mine was $159 plus shipping for a 90 day supply.

quote:

Originally posted by Butch 2340:
I take B12 that's about it. I find walking helps for some reason so I do a couple of miles on the treadmill each day.

Walking? Good Lord, If I walk more than 20 minutes non stop my feet are on fire! I take 1200 mg Gabapentin.
That being said, mornings are the worst. I pace the floor off and on for a little while and it limbers up my feet and I'm pretty good the rest of the day. And 2 Tylenol in the afternoon.
It is annoying!

I have neuropathy. No pain, but foot numbness that impairs my sense of balance. My neurologist says that nerves constricted where they exit the spine cause pain. Thankfully I don’t have that.

I walk at least two miles per day to practice dealing with the impairment. I once saw an unfortunate fellow that had both legs amputated below the knee. His shins were aluminum tubes. His feet were rubber appendages on the tubes. Yet he got along with the aid of a cane. I keep him in mind.

quote:

Originally posted by stiab:
Have been taking the EB-N6 for a month or so, can't tell a difference so far, but PN varies so much between people I would not let that deter you. Mine was $159 plus shipping for a 90 day supply.

Yes, that real world experience is important, my Doc said that it will either, help reduce it or help slow the growth so the future isn't as bad as it could be.

And that is the price, first batch the first 30 days are free plus $106 after to get the whole 90 day deal and $159 thereafter.

Did your PCP or Podiatrist say anything about his/her patients history with it... Mine inferred that many saw some relief.

quote:

Originally posted by HRK:

Did your PCP or Podiatrist say anything about his/her patients history with it... Mine inferred that many saw some relief.

Yes in some cases, but like I said earlier PN is so different among patients, you could have 100 people identify with PN but have 80 completely different situations. And for many of us it is not even the same day to day, which makes improvement hard to measure. A lot of it depends on what the source of the PN is. I was seen 30 years ago by the head of the neurology department at the medical school at Ohio State U, and he said mine was from a Guillain-Barre reaction, which would cause different nerve results from some other sources.

I have it, take Gabapentin, and wear snowmobile-boot-liners routinely to keep my feet warm. The warmth helps a LOT.