Anybody have one on their P365? Have them on a couple other carry guns and love them. Not great for longer ranges and target, but work great for us old geezers for EDC! Looking to put one on the P365.

I had them on a Glock once, the idea is nice but I found the "Dot the I" type sight acquisition a little slow and awkward to be honest.

I've had the plain white Big Dots on several other guns but I now prefer a large and also color contrasting site.
At the range a pistol is expected to be used at, they don't seem to reduce my accuracy.

I've got the 24/7 on my PPS M2 and I really like it!

Having difficulty finding at reasonable price; out of stock most places!

I've thought about trying them, but I don't like the idea that the rear sight is held on with just loctite and set screws.

You've got the set screws. Many after market sights are affixed in from with something like loc-tite.

I'm a big fan of Sig Classic Von Stavenhagen sights, so I thought I'd like the Big Dots, but I did not. Mostly, I didn't care for the wide V shape of the rear sight.

I have them on several pistols. I like them.

Mounted on a PPS M1 9.
Rapid target acquisition in full daylight and lower light situations.
I like them.