Thanks Rhino. I just missed it.

Glad to see the President and FDA are going ahead with use of chloroquine and hydroxychloroquine, which likely means FDA approval for on-label use; and potential compassionate use of remdesivir which is in clinical trials currently.

Here is a powerlineblog.com post that explains the issues related to accuracy of testing; and in particular explains well the Bayes theorem that highlights the potential negative effects of large numbers of false positive tests with disease that has a low prevalence.

Powerlineblog.com: Importance of accurate testing

https://www.breitbart.com/poli...-tremendous-results/

President Donald Trump promoted the use of the anti-malaria drug chloroquine at the White House on Thursday, the purpose of which is to treat people infected with the coronavirus.

“We’re going to be able to make that drug available almost immediately,” Trump said at the White House press briefing on Thursday.

Trump said that chloroquine was already developed, tested, and widely available to American doctors.

“The nice part is it’s been around for a long time, so we know that if things don’t go as planned, it’s not going to kill anybody,” Trump said. The president also mentioned the anti-viral drug Remdesivir produced by Gilead as a possible treatment drug.

FDA commissioner Stephen Hahn said that under the president’s direction he would move quickly for a chloroquine clinical trial to test its ability to treat the coronavirus.

In the meantime, doctors can ask for experimental drugs to use to treat their patients as part of a “compassionate use” program.

The president stated that anti-viral drugs had shown “very, very encouraging early results” in treatment tests.

xxxxxxxxxxxxxxx


https://www.breitbart.com/poli...onavirus-since-2005/

The world economy is collapsing because of the terror and mounting death toll caused by the Coronavirus pandemic. But the anti-malarial drug chloroquine is effective both as a prophylactic and treatment for the virus – and the medical establishment has known about this since at least the SARS coronavirus outbreak in 2005. What the hell is going on?

Yesterday, I reported the existence of three studies, all claiming that chloroquine phosphate had proved effective in treating the COVID-19.

This has since been confirmed by a more recent open-label non-randomised clinical trial in France by Didier Raoult​ M.D/Ph.D et al, completed just days ago. The sample was small but the results were convincing.

100% of patients that received a combination of HCQ and Azithromycin tested negative and were virologically cured within 6 days of treatment.

In addition, recent guidelines from South Korea and China report that hydroxychloroquine and chloroquine are effective antiviral therapeutic treatments for novel coronavirus.

But the story gets more extraordinary still. It turns out that the Centers for Disease Control and Prevention (CDC) has known since at least 2005 that chloroquine is effective against coronaviruses.

In 2005, Martin J Vincent et al published a study in Virology Journal titled ‘Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.

more at link

^^^ The French clinical study was submitted for publication review yesterday, this time involving Hydroxychloroquine and Azithromycin as a combination therapy, with positive results. While a 36 patient study (20 positives, 16 controls) the results are very encouraging:

https://drive.google.com/file/...um4xY_IlWSHnGbj/view

The addition of the antibiotic is meant to prevent the onset of pneumonia, potentially combat later stage respiratory infections and azithromycin has shown some antiviral activity in the past against two unrelated diseases. Figure 2 is most impressive if it holds for the general population.

BTW, not all Coronaviruses are the same so saying that a potential cure was known since 2005 is a bit misleading. Studies using Chloroquin began almost immediately once nCov-19 became a concern.

Will be interesting to see if the FDA allows the use of such antibiotic combination therapies for later-stage Covid-19 patients, excepting those that are allergic to mycins and potentially those patients with pre-existing heart conditions.

quote:

Originally posted by kkina:
Trump just announced that chloroquine has gotten the approval from the FDA and will be pushed out.

Not exactly how it works but lots going on behind the scenes.

quote:

Originally posted by SigSentry:

quote:

Originally posted by kkina:
Trump just announced that chloroquine has gotten the approval from the FDA and will be pushed out.

Not exactly how it works but lots going on behind the scenes.

Check out page 165.

quote:

It turns out that the Centers for Disease Control and Prevention (CDC) has known since at least 2005 that chloroquine is effective against coronaviruses.

In 2005, Martin J Vincent et al published a study in Virology Journal titled ‘Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.

Unbelievable... that's 15 years ago.
Yet, China wants to take credit for this.

quote:

Originally posted by sjtill:
A necessary skeptical view of the current lack of evidence needed for decision-making:

...

This has been posted several times in the last few pages.

I also posted an article from the same source that is a direct response to this one and takes the other viewpoint.

quote:

Originally posted by maladat:
This has been posted several times in the last few pages.

Yeah all the tail chasing between members makes most push the fast forward button past all the lovers' quarrels, re-quoting of all the quotes, one of those 'unintended consequences', eh?

quote:

chloroquine

Wait - is this why I can’t find any decent tonic water the last month?

A first-cousin of mine was tested officially in a local Doctors office this morning in metro Dallas, TX.

About a month ago he had what seemed and still seems like a regular upper respiratory infection.

Approximately 3wks ago he went to the Dr for it then, got a shot, some garden variety Rx, and off he went.

He has a wide friends, family, colleagues group in metro Dallas, and had many infection opportunities.

After his Dr visit I saw him twice at regional family things, and we're close so we hung out a while, many hours total. To date I feel nothing, fwiw. My only symptom of any sort is some annoying, seasonal, pollen sneezing...

But his is lingering, so he went back to the Doctor this morning, and the Doc suggested they test to be sure.

No one else in the family is reporting anything as of yet, btw, but there are many we need to check in with. But there are 8+ family members he's had contact with who are 60-76yo, most pretty healthy, though.

Anyway, they used some official test in a box, it was mailed off, and they will supposedly know the results in a week. He was asked to stay at home, wash his hands extra often, take more of the regular Rx he'd been on, wait...

Some relevant details: 39yo male, pretty healthy for a dude that never really exercises on purpose, etc, his only pre-existing condition is a slightly abnormal walk and cigarettes, but he gets around 90% normally. Fully employed, self employed, married with a kid in pre-school, not on the government train, etc.

Will post relevant updates as I have any.

I'm 50, myself, fwiw, and otherwise healthy. In an over abundance of caution I'm limiting my own travel and social interactions to a minimum and to those I've already been in contact with for this next week at least. We'll see how everyone feels and how his results come back.

No panic, no tone, no hysyeria, just deets...

Alighty then.

Italy currently has about half the number of confirmed cases of China, but Italy's death total is now slightly larger than China's.

China: 81,155 confirmed , 3,249 deaths

Italy: 41,035 confirmed , 3,405 deaths

quote:

Originally posted by sdy:
China: 81,155 confirmed , 3,249 deaths
Italy: 41,035 confirmed , 3,405 deaths

If you can believe anything coming out of China:

Global Pandemic Could Have Been Avoided If China Had Acted Sooner, Study Finds

Instead, the communist state lied and tried to cover it up...

It has become clear that the first cases of the Chinese virus were reported in mid-late November and early December, with scientists even estimating that the first jump of the virus from animals to humans probably occurred in October in the city of Wuhan.

Instead of acting immediately, the Chinese government waited until January 23rd before issuing quarantine orders to the 11 million people living in Wuhan.

The communist state was also actively working to suppress and punish doctors and scientists who tried to get warnings out, and lied to the world by claiming there was “no evidence” of human-to-human transmission.

https://www.zerohedge.com/geop...d-sooner-study-finds

I don't believe ANY numbers coming out of China. They have repeatedly lied and hid information for months.

I won't believe any of the numbers until the hindsight analysis and investigations, myself.

quote:

Originally posted by WaterburyBob:
I don't believe ANY numbers coming out of China. They have repeatedly lied and hid information for months.

Yeah, like they magically went to zero new cases.

Right.....

quote:

Originally posted by 46and2:
I won't believe any of the numbers until the hindsight analysis and investigations, myself.

I won't say I won't believe ANY of it, but having been around the block and time or three, I know the data & analysis is rife with issues and emotion of a thousand different sorts.

But to say that I'll reserve judgement until after the dust settles would be accurate.

I have maybe just a little more confidence in CDC numbers but not much.

Great, getting screwed over on the bailout, we'd be mostly phases out of bailout money, but they'll have no problem making me pay for it. All the years and years of paying my taxes and the time I need it, nope, sorry, can't help you. Where I live $75k a year is barely middle class, and is dirt poor in NYC or SF. Thanks government,.

McConnell's coronavirus stimulus plan would provide payments of $1,200 per person, $2,400 for couples

Either give it to everyone or means test it, this screws a lot of us in the middle. Giving it to fucking retirees? What income have they lost?

Hows about we just don't fucking pay them any more tax for the rest of the year. Then forever.

https://www.bbc.com/news/technology-51968302

Questions about internet load with everybody home, working remotely, watching streaming video, etc., have been mentioned in this thread before.

Netflix has just agreed to cut their streaming video bitrates (the effective "file size" of the streaming video) by 25% (meaning basically that video will be a little fuzzier) in Europe for the next 30 days in an effort to keep from overloading Europe's internet infrastructure.

It is mentioned in the article that Europe has seen a ~50% increase in internet bandwidth usage. I'm surprised it isn't higher.