“Multiple Americans have been cured of their diabetes after a groundbreaking trial has let them put down their insulin for good, researchers have announced. 

A team at the University of Chicago Medicine Transplant Institute has updated the results of the ongoing clinical trial of patients with type 1 diabetes.

Unlike type 2 diabetes, which typically comes on later in life and is caused by lifestyle factors such as obesity, type 1 diabetes, which affects as many as 4 million Americans, is an unpreventable autoimmune disorder in which the immune system destroys insulin-producing cells in the pancreas. …”

https://mol.im/a/15681835

Sounds promising. I have been a type 1 since I was 10 yrs old (52 yrs). It's the only life I know.

The cell therapy isn’t new. The immunosuppressant they used is the big deal as it’s so far less of a hammer than others. Time will tell. For reasonably well managed T1s the risks or immune supression outweigh the treatment they allow.

quote:

Originally posted by berto:
The cell therapy isn’t new. The immunosuppressant they used is the big deal as it’s so far less of a hammer than others. Time will tell. For reasonably well managed T1s the risks or immune supression outweigh the treatment they allow.

That's where I'm at. Having type 1 sucks, but being on immunosuppressants would be worse. I'm otherwise very healthy, and I'm not willing to compromise that. I've been kinda following this ..it'll be interesting to see how it plays out over the next couple of years.

Better to have no need for immunosuppressants at all. It’s still in its infancy but transplantation of slightly edited islet cells to have them evade the body’s immune response is very promising.

https://www.nejm.org/doi/abs/1...M.4M75AqemSuNaJpeWtc

This article has the latest update, this month: https://breakthrought1d.ca/cel...0no%20safety%20issue.

No immunosuppressants needed. That would be true cure, if large long-term clinical trials prove successful.