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Appendectomy may triple risk of Parkinson's

This topic can be found at:
https://sigforum.com/eve/forums/a/tpc/f/320601935/m/1120045654

May 09, 2019, 07:45 AM
Pipe Smoker
Appendectomy may triple risk of Parkinson's
“People who have their appendices taken out may be at higher risk of developing Parkinson's disease later in life, new research suggests.

A Case Western Reserve University and University Hospitals Cleveland Medical Center study of over 62 million patients found who that had had the operation were at a three-fold greater risk of developing Parkinson's.

Worldwide, over 10 million people have Parkinson's disease, a devastating neurological disease with no cure and struck comedian Robin Williams before his 2014 suicide.

The newly discovered link between the appendix and Parkinson's may provide a clue about when, where and why Parkinson's starts to develop…”

https://mol.im/a/7008055



Don’t argue with fools.
May 09, 2019, 08:11 AM
Gustofer
Researchers with too much time on their hands. Roll Eyes

Next they'll determine that those who have stubbed their toe in the past are more likely than not to develop hypertension later in life.


________________________________________________________
"Great danger lies in the notion that we can reason with evil." Doug Patton.
May 09, 2019, 08:11 AM
Sportshooter
When you lose a very angry appendix you lose a spectacular bellyache. YMMV
May 09, 2019, 08:34 AM
Powers77
As someone who had theirs out at 8 years old who has a father in late stages of Parkinson's this is of interest to me.
Ironically, I know that I recently saw a different study that claimed exactly the opposite correlation. Go figure.
May 09, 2019, 08:44 AM
justjoe
Hmmmm...something about correlation and causation here....


______________________________________________________

"You get much farther with a kind word and a gun than with a kind word alone."
May 09, 2019, 08:55 AM
RHINOWSO
Fuck, I'd be SOOOO much better off with that nearly burst thing in my gut!!! Big Grin Big Grin Big Grin
May 09, 2019, 09:06 AM
El Cid 92
Sarcasm on.....

Look at it this way. If you have your appendix and it gets infected, it'll "burst" and you'll get sepsis. Then likely die and not get Parkinson's. Valid data all around.

I think we are getting to the point where Stats can link anything and everything.

Andrew



Duty is the sublimest word in the English Language - Gen Robert E Lee.
May 09, 2019, 09:20 AM
RogueJSK
Exactly. I had mine out at 12 years old, but it was about to burst and kill me.

So I'll take the risk. If there even is a risk, and it's not just false correlation/causation assumptions.
May 09, 2019, 09:37 AM
MNSIG
I'm guessing there is some deeper link to an individual's response to chronic infection and inflammation which led to both conditions rather than a causal relationship. Of course, it makes great a click bait headline.
May 09, 2019, 11:01 AM
jhe888
Compared to years of Parkinsons, a relatively quick death from sepsis may be a choice some would make.




The fish is mute, expressionless. The fish doesn't think because the fish knows everything.
May 09, 2019, 11:03 AM
az4783054
Mine did burst at 17 years old. I vividly remember the pain and ER. I also drank milk during my childhood and coffee in adulthood. There is probably another correlation.

My wife's Uncle eventually died of complications of Parkinson's. He was very active.

This message has been edited. Last edited by: az4783054,


I've enjoyed my time here, but tired of the whining and general management. Time to move on.
May 09, 2019, 11:04 AM
parabellum
Well, yes, dying from appendicitis does dramatically reduce your chances of developing Parkinson's Disease.

??
May 09, 2019, 11:12 AM
parabellum
quote:
Originally posted by jhe888:
Compared to years of Parkinsons, a relatively quick death from sepsis may be a choice some would make.
...said the man who is not in that position.

It's very easy to sit at your computer and make such suppositions. You wouldn't know how you would react until you were faced with this.


____________________________________________________

"I am your retribution." - Donald Trump, speech at CPAC, March 4, 2023
May 09, 2019, 11:40 AM
1s1k
It's not like you have a choice in the matter.
May 09, 2019, 12:06 PM
oldRoger
quote:
Worldwide, over 10 million people have Parkinson's disease, a devastating neurological disease with no cure


This may be true and might even be under reported, however, with something like 6 billion people living, Parkinson's is hardly a high risk. So even if (big "if" there since correlation does not equal causation) your risk is tripled it is still not high. Risk from death due to a ruptured appendix on the other hand is very, very high.
May 09, 2019, 12:20 PM
Pipe Smoker
The appendix has long been considered to be a vestigial organ with no purpose. But several months ago I read that a purpose has been discovered. When all of the (very beneficial) gut bacteria has been lost from the intestines, the appendix serves as a reservoir for the bacteria, from which the bacteria can repopulate the intestines.

The total loss of gut bacteria can occur as a result of severe diarrhea. Also, I suspect, as a result of a pre-colonoscopy gut purge. That’s one reason why I’ll never have another colonoscopy. I’ll rely on an annual poop kit check instead. The diagnostic reliability of poop kit checks is much improved in recent years. An annual poop kit check might even be better than a colonoscopy at several-year intervals.

Obviously, appendicitis mandates an appendectomy, over all other considerations.



Don’t argue with fools.
May 09, 2019, 01:15 PM
berto
Dead at 16 or still kicking at 45 with maybe an increased risk of Parkinson's? Hmmm, tough call that one. Get the time machine ready in case I want to go back and be dead.
May 09, 2019, 01:22 PM
FenderBender
3 times more likely, however it's still under one percent.


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The point is, who will stop me?
May 09, 2019, 01:24 PM
RHINOWSO
"Hey, saving your life years ago may fuck you up in 50 years - so THINK ABOUT IT!!!!"

LMFAO.

Mine didn't burst but the old Surgeon who took it out said it was "just about to pop". I felt like death all morning and couldn't walk, then my parents took me to the hospital - they had me under the knife in about an hour.
May 09, 2019, 01:30 PM
GrumpyBiker
Anyone else remember the medical community arguing over whether the simple egg was either good or death on a plate and how many times the “facts” flipped the decision one way then the other?

It’s interesting, as mine postponed my departure to Parris Island for 6 months but I’m not on pins & needles with worry just yet.




U.S.M.C.
VFW-8054
III%

"Never let a Wishbone grow where a Backbone should be "